Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522293 | 0.84 | MEN1 (0.49) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL28870957 | 0.82 | HTT (0.62) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL9520962 | 0.81 | SMN1; SMN2 (0.42) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL8363953 | 0.79 | ADORA2A (0.44) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL28186628 | 0.77 | ALDH1A1 (0.55) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL6079917 | 0.76 | ADORA2A (0.57) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL2550277 | 0.76 | ADORA2A (0.62) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL21144033 | 0.75 | ADORA2A (0.54) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL3360852 | 0.72 | ADORA2A (0.56) | ADORA2AHTTLMNAADORA3ADORA2B | |
| SCHEMBL26098451 | 0.72 | KDM4E (0.41) | ADORA2AHTTLMNAADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250998-B1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| CN-101938988-B | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| CN-101938988-A | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2011-01-05 | — | — | CN | disclosed |
| EP-2250998-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
| CN-1071424-A | Pyrazole derivatives and agricultural or horticultural bactericide thereof | NIPPON SODA CO (JP) | 1993-04-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, RTN3 | ADORA2A 647/4885HTT 3402/4885LMNA 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.