Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518040 | 0.83 | GAA (0.61) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL9182795 | 0.82 | GSR (0.61) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL8843395 | 0.80 | GSR (0.54) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL284696 | 0.79 | ALDH1A1 (0.63) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL4569533 | 0.79 | GAA (0.83) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL9517378 | 0.79 | GAA (0.57) | GAAKMT2AGSRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8940787 | 0.79 | GSR (0.56) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL17550780 | 0.79 | GSR (0.53) | GAAKMT2AGSRALDH1A1LMNA | |
| SCHEMBL11703395 | 0.78 | GAA (0.72) | GAAKMT2AGSRMEN1MAPT | |
| SCHEMBL11658045 | 0.78 | GAA (0.56) | GAAKMT2AGSRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404039-B1 | PHARMACEUTICALS CONTAINING DI-TERT.BUTYLHYDROXYPHENYL-DERIVATIVES AND NEW DERIVATIVES | Roche Diagnostics GmbH (DE) | 1993-01-13 | — | — | EP | claimed |