Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8940787 | 0.98 | GSR (0.56) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9182795 | 0.86 | GSR (0.61) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL284696 | 0.83 | ALDH1A1 (0.63) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL17550780 | 0.83 | GSR (0.53) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9185815 | 0.81 | GSR (0.56) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9518040 | 0.80 | GAA (0.61) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9185437 | 0.80 | GSR (0.54) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9520969 | 0.80 | GAA (0.54) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL8844415 | 0.80 | MAPT (0.66) | ALDH1A1TSHRLMNAMAPK1CYP1A2 | |
| SCHEMBL7511206 | 0.80 | GSR (0.62) | GSRGAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633283-A | Method for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1997-05-27 | — | — | US | claimed |
| US-5552439-A | AMINOPHENOL DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | claimed |
| EP-0722723-A2 | Phenol derivatives for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | claimed |
| EP-0474403-B1 | Method of treating inflammatory bowel disease | LILLY CO ELI (US) | 1995-05-10 | — | — | EP | claimed |
| US-5281623-A | Administering amino substituted phenolic derivatives as antiinflammatory or antiarthritic agents | ELI LILLY AND COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| EP-0474403-A1 | Method of treating inflammatory bowel disease | ELI LILLY AND COMPANY (US) | 1992-03-11 | — | — | EP | claimed |
| US-5633283-A | Method for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5552439-A | AMINOPHENOL DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0722723-A2 | Phenol derivatives for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| EP-0680755-A1 | Method for treating inflammation, ischemia-induced cell damage and muscular dystrophy | ELI LILLY AND COMPANY (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0474403-B1 | Method of treating inflammatory bowel disease | LILLY CO ELI (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5393786-A | Administering certain phenolic compounds | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5281623-A | Administering amino substituted phenolic derivatives as antiinflammatory or antiarthritic agents | ELI LILLY AND COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5280046-A | Using an amide containing phenol compound | THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0500336-A1 | Composition containing certain phenol and benzamide for the treatment of type I diabetes | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0476846-A2 | Method for treating imflammation, ischemia-induced cell damage and muscular dystrophy | ELI LILLY AND COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0474403-A1 | Method of treating inflammatory bowel disease | ELI LILLY AND COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |