Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.53 |
| ▸ | C3AR1 | Q16581 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520578 | 0.99 | TBXAS1 (0.55) | TBXAS1C3AR1ALDH1A1LMNAPTAFR | |
| SCHEMBL10399364 | 0.96 | TBXAS1 (0.51) | TBXAS1C3AR1ALDH1A1LMNAFKBP1A | |
| SCHEMBL10399365 | 0.96 | TBXAS1 (0.51) | TBXAS1C3AR1ALDH1A1LMNAFKBP1A | |
| SCHEMBL10398309 | 0.95 | TBXAS1 (0.52) | TBXAS1C3AR1ALDH1A1LMNA | |
| SCHEMBL10398308 | 0.95 | TBXAS1 (0.52) | TBXAS1C3AR1ALDH1A1LMNA | |
| SCHEMBL9519851 | 0.94 | TBXAS1 (0.57) | TBXAS1PTAFRTDP1L3MBTL1 | |
| SCHEMBL10397782 | 0.90 | TBXAS1 (0.55) | TBXAS1PTAFRTDP1L3MBTL1 | |
| SCHEMBL10397781 | 0.90 | TBXAS1 (0.55) | TBXAS1PTAFRTDP1L3MBTL1 | |
| SCHEMBL8503785 | 0.84 | CYP2C9 (0.52) | TBXAS1C3AR1ALDH1A1 | |
| SCHEMBL7539729 | 0.83 | EPHX2 (0.54) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |