Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652285 | 0.91 | L3MBTL1 (0.52) | EPHX2L3MBTL1HTTEPHX1TAAR1 | |
| SCHEMBL10399364 | 0.86 | TBXAS1 (0.51) | — | |
| SCHEMBL10399365 | 0.86 | TBXAS1 (0.51) | — | |
| SCHEMBL8129250 | 0.85 | CPN1 (0.50) | EPHX2SMN1; SMN2GRIK1 | |
| SCHEMBL10398309 | 0.85 | TBXAS1 (0.52) | — | |
| SCHEMBL10398308 | 0.85 | TBXAS1 (0.52) | — | |
| SCHEMBL9521048 | 0.83 | TBXAS1 (0.53) | L3MBTL1 | |
| SCHEMBL9520578 | 0.81 | TBXAS1 (0.55) | L3MBTL1 | |
| SCHEMBL27495306 | 0.81 | CYP2C9 (0.61) | EPHX2EPHX1TAAR1CYP2C9CYP2C19 | |
| SCHEMBL7380729 | 0.79 | ACE (0.49) | EPHX2L3MBTL1HTTEPHX1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |