Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19474859 | 0.82 | KMT2A (0.69) | KMT2AMEN1TP53POLBHSD17B10 | |
| SCHEMBL9126573 | 0.81 | NPC1 (0.60) | MAPTRXFP1KMT2AMEN1NPC1 | |
| SCHEMBL9125080 | 0.79 | ALDH1A1 (0.54) | MAPTKMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL9125047 | 0.79 | P2RX1 (0.65) | RXFP1 | |
| SCHEMBL9125687 | 0.79 | ALDH1A1 (0.50) | MAPTRXFP1KMT2ANPC1POLB | |
| SCHEMBL9125691 | 0.79 | GAA (0.50) | NR1H4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8939689 | 0.77 | HPGD (0.53) | MAPTKMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL5666065 | 0.76 | MAPT (0.67) | MAPTRXFP1NR1H4USP2KMT2A | |
| SCHEMBL9123251 | 0.75 | GAA (0.62) | MAPTKMT2ANPC1TP53POLB | |
| SCHEMBL9125076 | 0.75 | KMT2A (0.57) | MAPTKMT2AMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |