Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939600 | 0.82 | LMNA (0.50) | HPGDGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL9413478 | 0.80 | HSD17B2 (0.38) | GAAKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL9413481 | 0.80 | HTR6 (0.39) | GAAKMT2ALMNAALDH1A1HTT | |
| SCHEMBL9521185 | 0.77 | MAPT (0.58) | GAAKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL8939599 | 0.72 | ALDH1A1 (0.45) | GAAKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8939694 | 0.70 | GAA (0.38) | GAAKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL8939684 | 0.70 | LMNA (0.47) | HPGDGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL8939671 | 0.69 | ALDH1A1 (0.50) | HPGDGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL8939618 | 0.69 | ALDH1A1 (0.44) | GAAKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL11351755 | 0.68 | GAA (0.53) | HPGDGAAKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |