Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520878 | 1.00 | TAS1R3 (0.44) | TAS1R3TAS1R1GAAMAPTCES2 | |
| SCHEMBL10397681 | 0.86 | TAS1R3 (0.46) | TAS1R3TAS1R1GAAMAPTCES2 | |
| SCHEMBL10397682 | 0.86 | TAS1R3 (0.46) | TAS1R3TAS1R1GAAMAPTCES2 | |
| Bicarbonate SCHEMBL9520886 | 0.86 | TAS1R3 (0.46) | TAS1R3TAS1R1GAAMAPTCES2 | |
| SCHEMBL10397683 | 0.86 | TAS1R3 (0.46) | TAS1R3TAS1R1GAAMAPTCES2 | |
| Bicarbonate SCHEMBL9521205 | 0.86 | TAS1R3 (0.46) | TAS1R3TAS1R1GAAMAPTCES2 | |
| SCHEMBL9520959 | 0.85 | PDE4B (0.46) | TAS1R3TAS1R1PARP1NPC1RAB9A | |
| SCHEMBL10514298 | 0.83 | TAS1R3 (0.44) | TAS1R3TAS1R1GAAMAPTCES2 | |
| SCHEMBL10514300 | 0.83 | TAS1R3 (0.44) | TAS1R3TAS1R1GAAMAPTCES2 | |
| SCHEMBL10398897 | 0.82 | TAS1R3 (0.48) | TAS1R3TAS1R1GAAMAPTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |