Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 8/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410241 | 0.93 | HTR3A (0.33) | HTR3AHPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL9521366 | 0.91 | HTR3A (0.31) | HTR3AMAPTTSHRDHODH | |
| SCHEMBL9523121 | 0.89 | HPGD (0.35) | HTR3AHPGDSMN1; SMN2MAPTDHODH | |
| SCHEMBL9520464 | 0.88 | HTR3A (0.35) | HTR3AHPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL9520857 | 0.88 | HPGD (0.35) | HTR3AHPGDSMN1; SMN2MAPTDHODH | |
| SCHEMBL9520790 | 0.88 | HPGD (0.35) | HTR3AHPGDSMN1; SMN2MAPTDHODH | |
| SCHEMBL10412010 | 0.85 | KDM4E (0.32) | HPGDSMN1; SMN2TSHR | |
| SCHEMBL10410377 | 0.84 | HPGD (0.31) | HTR3AHPGDSMN1; SMN2 | |
| SCHEMBL10410736 | 0.82 | — | — | |
| SCHEMBL10411959 | 0.82 | HTR3A (0.34) | HTR3ASMN1; SMN2MAPTDHODHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |