Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520592 | 0.91 | MAPT (0.32) | HTR3AHPGDSMN1; SMN2TSHRMAPT | |
| SCHEMBL9521255 | 0.88 | HPGD (0.37) | HTR3AHPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL9521287 | 0.88 | HTR3A (0.33) | HTR3AHPGDSMN1; SMN2TSHRMAPT | |
| SCHEMBL9522986 | 0.88 | MAPT (0.38) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9521382 | 0.88 | MAPT (0.38) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10410241 | 0.87 | HTR3A (0.33) | HTR3AHPGDSMN1; SMN2TSHRMAPT | |
| SCHEMBL22745804 | 0.80 | MAPT (0.36) | HPGDSMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9523079 | 0.79 | MEN1 (0.33) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9521057 | 0.79 | GAA (0.38) | HTR3AHPGDSMN1; SMN2MAPTGAA | |
| SCHEMBL9519865 | 0.79 | PPOX (0.35) | HPGDSMN1; SMN2MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |