Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518430 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL9518460 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPK1KMT2AMAOBHRH4 | |
| SCHEMBL9519552 | 0.72 | MAOB (0.31) | MAOB | |
| SCHEMBL17531792 | 0.72 | KMT2A (0.38) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL17531785 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPK1KMT2AMAOB | |
| Hydrochloric Acid SCHEMBL9518424 | 0.71 | ALDH1A1 (0.31) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL9518264 | 0.71 | ALDH1A1 (0.32) | ALDH1A1MAPK1KMT2AMAOB | |
| Hydrochloric Acid SCHEMBL10543233 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL12214468 | 0.69 | HTR2A (0.37) | ALDH1A1MAPK1KMT2ATSHR | |
| SCHEMBL10791376 | 0.67 | TSHR (0.42) | ALDH1A1MAPK1CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |