Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10543233 | 0.99 | ALDH1A1 (0.34) | ALDH1A1MAPK1KMT2ACPB1CPB2 | |
| SCHEMBL9518250 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPK1KMT2AMAOBPOLB | |
| Hydrochloric Acid SCHEMBL10542612 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPK1KMT2AMAOBPOLB | |
| SCHEMBL9518304 | 0.74 | PDE3B (0.38) | PDE3BPDE3A | |
| SCHEMBL17531792 | 0.71 | KMT2A (0.38) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL9521350 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL11048752 | 0.67 | CPB1 (0.43) | ALDH1A1MAPK1KMT2ACPB1CPB2 | |
| SCHEMBL11046403 | 0.67 | CPB1 (0.54) | CPB1CPB2PDE3BPDE3A | |
| SCHEMBL10801359 | 0.66 | MAOB (0.37) | ALDH1A1MAPK1KMT2AMAOB | |
| SCHEMBL12191290 | 0.65 | HTR1A (0.37) | ALDH1A1MAPK1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |