Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521064 | 0.90 | ADRA1A (0.60) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| SCHEMBL9521449 | 0.89 | ADRA1A (0.50) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| Alcohol SCHEMBL10441619 | 0.84 | ADRA1A (0.42) | ADRA1APDE4D | |
| SCHEMBL9523192 | 0.84 | ADRA1A (0.49) | ADRA1APDE4DSMN1; SMN2TSHR | |
| SCHEMBL9521958 | 0.83 | ADRA1A (0.34) | ADRA1APDE4D | |
| SCHEMBL9520374 | 0.79 | ADRA1A (0.39) | ADRA1APDE4D | |
| Isoprothiolane SCHEMBL8408577 | 0.79 | ADRA1A (0.60) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| Isoprothiolane SCHEMBL71267 | 0.79 | ADRA1A (0.60) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| SCHEMBL8055886 | 0.78 | ADRA1A (0.82) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| SCHEMBL9523261 | 0.77 | ADRA1A (0.42) | ADRA1APDE4DGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2223578-A | — | — | None | — | — | JP | disclosed |
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
| JP-H02223578-A | THIOKETENE DERIVATIVE AND PRODUCTION THEREOF | YUHAN CORP | 1990-09-05 | — | — | JP | disclosed |
| EP-0366614-A2 | Pharmaceutically active dithioketene derivatives | YUHAN CORPORATION, LTD. (KR) | 1990-05-02 | — | — | EP | disclosed |