SCHEMBL9521668

SCHEMBL9521668

C=CCN(C(=O)c1cccc2nnsc12)S(=O)(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
RAB9A P51151 2/20 0.36
ESR1 P03372 1/20 0.36
HSD11B1 P28845 2/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 3/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
HPGD P15428 1/20 0.35
C5AR1 P21730 1/20 0.32
POLB P06746 2/20 0.32
S1PR1 P21453 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PTPN1 P18031 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9520328 0.82 KMT2A (0.39) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL9452981 0.80 MEN1 (0.46) KMT2AMEN1ALDH1A1KDM4ELMNA
SCHEMBL11437067 0.75 CYP1A2 (0.43) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL11442731 0.73 HSD11B1 (0.63) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL626506 0.70 S1PR1 (0.40) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL11435843 0.69 S1PR1 (0.44) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL11440787 0.69 FLT1 (0.48) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL2237002 0.69 ESR1 (0.49) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL25702589 0.69 RAB9A (0.51) KMT2AMEN1RAB9AESR1HSD11B1
SCHEMBL11435835 0.69 ESR1 (0.44) KMT2AMEN1RAB9AESR1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384889-B1 AGENT TO PROTECT PLANTS AGAINST DISEASES CIBA-GEIGY AG (CH) 1993-10-13 EP claimed
US-5051436-A Heterocyclic substituted benzothiadiazoles as viricides, fungicides and bactericides CIBA-GEIGY CORPORATION (US) 1991-09-24 US disclosed