Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917313 | 0.82 | TAAR1 (0.50) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL11462574 | 0.78 | ALDH1A1 (0.49) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL25341473 | 0.78 | ALDH1A1 (0.49) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL3408632 | 0.78 | SLC6A2 (0.63) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL8154724 | 0.74 | TAAR1 (0.47) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL19841922 | 0.74 | SLC6A4 (0.52) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL23467849 | 0.74 | TAAR1 (0.42) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL11059680 | 0.73 | TAAR1 (0.50) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 | |
| SCHEMBL2135113 | 0.72 | TAAR1 (0.68) | TAAR1SLC6A4AOC3MIFMAOB | |
| SCHEMBL24067332 | 0.72 | CNR1 (0.49) | TAAR1SLC6A2SLC6A3HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544819-A4 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | — | 1993-10-20 | — | — | EP | disclosed |
| EP-0544819-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1993-06-09 | — | — | EP | disclosed |