SCHEMBL2135113

SCHEMBL2135113

Clc1ccc(CCc2ccc(Cl)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.68
IDO1 P14902 5/20 0.58
LMNA P02545 1/20 0.57
CYP2A6 P11509 1/20 0.57
MAOB P27338 1/20 0.56
AOC3 Q16853 1/20 0.54
HTR3E A5X5Y0 1/20 0.52
HTR3B O95264 1/20 0.52
HTR3A P46098 1/20 0.52
HTR3D Q70Z44 1/20 0.52
HTR3C Q8WXA8 1/20 0.52
MIF P14174 1/20 0.52
DAO P14920 2/20 0.50
AGXT P21549 2/20 0.50
SLC6A4 P31645 1/20 0.50
IGF1R P08069 1/20 0.50
ALOX15 P16050 1/20 0.50
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8196751 0.88 SIGMAR1 (0.58) TAAR1LMNAMAOBALOX15
SCHEMBL16663974 0.88 TAAR1 (0.56) TAAR1IDO1LMNACYP2A6MAOB
SCHEMBL10365734 0.87 IGF1R (0.64) TAAR1IDO1LMNACYP2A6MAOB
SCHEMBL18050371 0.87 TAAR1 (0.62) TAAR1IDO1LMNACYP2A6MAOB
SCHEMBL18550393 0.86 TAAR1 (0.54) TAAR1IDO1LMNAMAOBAOC3
SCHEMBL8584816 0.86 TAAR1 (0.54) TAAR1IDO1LMNACYP2A6MAOB
SCHEMBL12809556 0.86 CNR2 (0.55) TAAR1IDO1CYP2A6MAOBAOC3
SCHEMBL5647781 0.86 ESR1 (0.74) TAAR1HTR3AIGF1RALOX15GFER
Ammonia Solution, Strong SCHEMBL11188168 0.86 SIGMAR1 (0.56) TAAR1LMNAMAOBALOX15
SCHEMBL16663705 0.86 TAAR1 (0.54) TAAR1IDO1MAOBAOC3HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN claimed
CN-119263950-A Synthesis method of 1, 2-bis (4-vinyl phenyl) ethane 上海康鹏科技股份有限公司 2025-01-07 CN claimed
CN-117264211-A Low-melting-point polyarylene sulfide resin and film, and preparation methods and applications thereof 新凝合科技(成都)有限公司 2023-12-22 CN claimed
CN-119263950-A Synthesis method of 1, 2-bis (4-vinyl phenyl) ethane 上海康鹏科技股份有限公司 2025-01-07 CN disclosed
CN-117567331-A Synthesis method of 1, 2-dithioethane compound and 1, 4-dithiane 河北北方学院 2024-02-20 CN disclosed
CN-117264211-A Low-melting-point polyarylene sulfide resin and film, and preparation methods and applications thereof 新凝合科技(成都)有限公司 2023-12-22 CN disclosed
US-11773045-B2 Acid-catalyzed photocatalyzed oxidation reaction of benzylic C—H bonds of aromatic compound NANJING TECH UNIVERSITY (CN) 2023-10-03 US disclosed
US-20230242470-A1 ACID-CATALYZED PHOTOCATALYZED OXIDATION REACTION OF BENZYLIC C-H BONDS OF AROMATIC COMPOUND NANJING TECH UNIVERSITY (CN) 2023-08-03 US disclosed
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2023-07-13 US disclosed
CN-114507109-B Method for synthesizing bibenzyl compound by photocatalysis 苏州大学张家港工业技术研究院 2023-06-23 CN disclosed
US-11655217-B2 Pyrazole MAGL inhibitors H. LUNDBECK A/S (DK) 2023-05-23 US disclosed
WO-2010117285-A2 PROCESS FOR THE PREPARATION OF GRIGNARD COMPOUNDS ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) 2010-10-14 WO disclosed
EP-1861376-A1 CIS-2,4,5-TRIARYL-IMIDAZOLINES AND THEIR USE AS ANTI-CANCER MEDICAMENTS F. Hoffmann-Roche AG (CH) 2007-12-05 EP disclosed
US-7304103-B2 One step; high functionality; maintains critical properties; polymer composite materials, molecular electronics, sensor devices WILLIAM MARSH RICE UNIVERSITY (US) 2007-12-04 US disclosed
WO-2006097261-A1 CIS-2,4,5-TRIARYL-IMIDAZOLINES AND THEIR USE AS ANTI-CANCER MEDICAMENTS F.HOFFMANN-LA ROCHE AG (CH) 2006-09-21 WO disclosed
EP-1458677-A1 3-PHENYL-2-ARYLALKYLTHIOPROPIONIC ACID DERIVATIVES AS SELECTIVE AGONISTS OF PPAR-ALPHA Astrazeneca AB (SE) 2004-09-22 EP disclosed
WO-2003051826-A1 3-PHENYL-2-ARYLALKYLTHIOPROPIONIC ACID DERIVATIVES AS SELECTIVE AGONISTS OF PPAR-ALPHA ASTRAZENECA AB (SE) 2003-06-26 WO disclosed
US-5093046-A Suppression of dimerization BASF AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
EP-0415247-A2 Process for the preparation of ether solutions of arylmethylmagnesium halides BASF Aktiengesellschaft (DE) 1991-03-06 EP disclosed
US-4585594-A CARBONYLATION OF ALLYL ALCOHOL DERIVATIVE BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL TAAR1 2957/4885IDO1 3336/4885LMNA 2986/4885
US-11655217-B2 Pyrazole MAGL inhibitors MGLL, PNLIP, LPL TAAR1 2850/4885IDO1 3331/4885LMNA 3058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.