Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 1.00 |
| ▸ | ACHE | P22303 | 6/20 | 0.98 |
| ▸ | MAOB | P27338 | 4/20 | 0.98 |
| ▸ | BCHE | P06276 | 2/20 | 0.98 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030976 | 0.99 | SIGMAR1 (1.00) | SIGMAR1ACHEMAOBBCHEHRH3 | |
| SCHEMBL28030948 | 0.98 | SIGMAR1 (1.00) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28031516 | 0.89 | SIGMAR1 (0.83) | SIGMAR1ACHEMAOBBCHEHRH3 | |
| SCHEMBL28030968 | 0.88 | SIGMAR1 (1.00) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28030971 | 0.88 | SIGMAR1 (0.82) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL9426312 | 0.87 | SIGMAR1 (0.78) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL7899445 | 0.86 | SIGMAR1 (0.82) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL10518678 | 0.84 | SIGMAR1 (0.75) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL10519899 | 0.80 | MAOB (0.69) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28031514 | 0.79 | SIGMAR1 (0.83) | SIGMAR1ACHEMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533804-A4 | SIGMA BINDING SITE AGENTS | — | 1993-04-21 | — | — | EP | claimed |