Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.82 |
| ▸ | ACHE | P22303 | 6/20 | 0.82 |
| ▸ | MAOB | P27338 | 3/20 | 0.82 |
| ▸ | BCHE | P06276 | 2/20 | 0.82 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031516 | 0.96 | SIGMAR1 (0.83) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28030971 | 0.95 | SIGMAR1 (0.82) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28030976 | 0.87 | SIGMAR1 (1.00) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL9521742 | 0.86 | SIGMAR1 (1.00) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28031514 | 0.86 | SIGMAR1 (0.83) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL28030948 | 0.85 | SIGMAR1 (1.00) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL10517295 | 0.84 | DRD2 (0.67) | SIGMAR1ACHEBCHE | |
| SCHEMBL10518674 | 0.83 | SIGMAR1 (0.61) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL10518188 | 0.82 | SIGMAR1 (0.62) | SIGMAR1ACHEMAOBBCHE | |
| SCHEMBL10518095 | 0.82 | SIGMAR1 (0.59) | SIGMAR1ACHEMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187793-B1 | PSYCHOSIS, SCHIZOPHRENIA; ANTIALLERGENS | FERRER INTERNACIONAL, S.A. (ES) | 2001-02-13 | — | — | US | disclosed |