Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400974 | 0.73 | PARP1 (0.47) | HTR2CHTR2AHTR2BPARP1NAMPT | |
| SCHEMBL11242393 | 0.72 | HTR2C (0.49) | HTR2CHTR2AHTR2BPARP1 | |
| Hydrochloric Acid SCHEMBL11101784 | 0.72 | PARP1 (0.46) | HTR2CHTR2AHTR2BPARP1NAMPT | |
| SCHEMBL7985474 | 0.71 | HTR2C (0.50) | HTR2CHTR2AHTR2BKMT2APARP1 | |
| SCHEMBL11665238 | 0.67 | HTR2C (0.40) | HTR2CHTR2AHTR2BALDH1A1PARP1 | |
| SCHEMBL12537066 | 0.67 | HTR2C (0.46) | HTR2CHTR2AHTR2BKMT2APARP1 | |
| SCHEMBL3070795 | 0.66 | HRH3 (0.51) | HTR2CHTR2AHTR2BKMT2ASIGMAR1 | |
| SCHEMBL38662568 | 0.66 | PIM1 (0.49) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL28229327 | 0.65 | NPC1 (0.44) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL14069048 | 0.65 | HTR2C (0.46) | HTR2CHTR2AHTR2BPARP1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557289-A1 | 4-(1,2-BENZISOXAZOLYL)PIPERIDINE ANTIPSYCHOTIC AGENTS. | PFIZER (US) | 1993-09-01 | — | — | EP | claimed |