Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333433 | 0.87 | — | — | |
| SCHEMBL7766629 | 0.82 | — | — | |
| SCHEMBL11757421 | 0.73 | CYP2C9 (0.37) | ALDH1A1HPGDNPSR1L3MBTL1 | |
| SCHEMBL458091 | 0.71 | — | — | |
| SCHEMBL6666874 | 0.69 | — | — | |
| SCHEMBL10752817 | 0.69 | — | — | |
| SCHEMBL1897982 | 0.69 | — | — | |
| SCHEMBL7131864 | 0.68 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL7131868 | 0.68 | HTR1B (0.32) | — | |
| SCHEMBL4563307 | 0.68 | NPSR1 (0.41) | ALDH1A1HPGDNPSR1L3MBTL1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269308-B1 | PROCESS FOR THE SYNTHESIS OF 4-AMINO-1,2,4-(4H)TRIAZOLE DERIVATIVES | REILLY INDUSTRIES, INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5099028-A | Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivatives | REILLY TAR AND CHEMICAL CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0269308-A2 | Process for the synthesis of 4-amino-1,2,4-(4H)triazole derivatives | REILLY INDUSTRIES, INC. (US) | 1988-06-01 | — | — | EP | disclosed |