SCHEMBL458091

SCHEMBL458091

C=CCc1nnn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9441460 0.77
SCHEMBL308710 0.76
SCHEMBL9522589 0.71 ALDH1A1 (0.32)
SCHEMBL14514225 0.69
SCHEMBL523100 0.68
SCHEMBL2800481 0.67
SCHEMBL5318623 0.65
SCHEMBL29748 0.64
SCHEMBL9441455 0.64
SCHEMBL1128201 0.62 L3MBTL1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP claimed
US-11618753-B2 Aminopyrrolotriazines as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2023-04-04 US claimed
CN-112680228-B Etching composition for silicon nitride layer and method for etching silicon nitride layer using the same 三星SDI株式会社 2022-04-19 CN claimed
US-11254871-B2 Etching composition for silicon nitride layer and method of etching silicon nitride layer using the same SAMSUNG SDI CO., LTD. (KR) 2022-02-22 US claimed
US-20210115335-A1 ETCHING COMPOSITION FOR SILICON NITRIDE LAYER AND METHOD OF ETCHING SILICON NITRIDE LAYER USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2021-04-22 US claimed
CN-112680228-A Etching composition for silicon nitride layer and method for etching silicon nitride layer using the same 三星SDI株式会社 2021-04-20 CN claimed
EP-3743430-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2020-12-02 EP claimed
US-20200347071-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2020-11-05 US claimed
US-20190315693-A1 APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF RES TRIANGLE INST (US) 2019-10-17 US claimed
US-10377718-B2 Apelin receptor (APJ) agonists and uses thereof RESEARCH TRIANGLE INSTITUTE (US) 2019-08-13 US claimed
WO-1990002558-A1 ELASTASE INHIBITING POLYMERS AND METHODS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1990-03-22 WO claimed
US-4643991-A TREATMENT OF EMPHYSEMA THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1987-02-17 US claimed
EP-0068466-B1 4-ARYL OR HETEROARYL THIO-2-OXO-1-AZETIDINESULFONIC ACID SALTS AND PROCESS FOR THEIR PREPARATION E.R. Squibb &amp; Sons, Inc. (US) 1987-01-14 EP claimed
EP-0150891-A1 Tricyclic compounds, processes for their preparation, compositions containing such compounds and their use in medicine THE WELLCOME FOUNDATION LIMITED (GB) 1985-08-07 EP claimed
EP-0090366-A1 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-10-05 EP claimed
US-4177257-A ANTIANAPHYLACTIC AGENTS BURROUGHS WELLCOME CO. (US) 1979-12-04 US claimed
US-4165429-A 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1979-08-21 US claimed
US-4103015-A TRICYCLIC THIOXANTHONE-10,10-DIOXIDES BURROUGHS WELLCOME CO. (US) 1978-07-25 US claimed
US-3978050-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1976-08-31 US claimed
US-3950330-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1976-04-13 US claimed