Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604115 | 0.79 | NPSR1 (0.35) | NPSR1HPGDALDH1A1L3MBTL1MCL1 | |
| Hydrochloric Acid SCHEMBL31098159 | 0.78 | LMNA (0.32) | NPSR1 | |
| SCHEMBL2020536 | 0.72 | — | — | |
| SCHEMBL24065806 | 0.70 | — | — | |
| SCHEMBL10910403 | 0.70 | NPSR1 (0.35) | NPSR1HPGDALDH1A1L3MBTL1MCL1 | |
| Hydrochloric Acid SCHEMBL1365937 | 0.68 | CACNA1H (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL3703329 | 0.68 | GLA (0.40) | ALDH1A1KDM4E | |
| SCHEMBL9522589 | 0.68 | ALDH1A1 (0.32) | NPSR1HPGDALDH1A1L3MBTL1MCL1 | |
| SCHEMBL9726802 | 0.67 | NPSR1 (0.33) | NPSR1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL20470648 | 0.67 | SMN1; SMN2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061464-A2 | COMBINATION THERAPY FOR TUMORAL DISEASE TREATMENT | Ramot, at Tel Aviv University Ltd. (IL) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008032324-A2 | COMBINATION THERAPY FOR TUMORAL DISEASE TREATMENT | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2008-03-20 | — | — | WO | disclosed |
| EP-0088595-A2 | Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
| EP-0050558-A2 | Photographic emulsions and elements capable of forming direct-positive images | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-04-28 | — | — | EP | disclosed |