Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521451 | 1.00 | KCNH2 (0.49) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL2124132 | 0.85 | KCNH2 (0.49) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL24516887 | 0.84 | FNTA (0.60) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL9790119 | 0.84 | FNTA (0.60) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL15709400 | 0.84 | FNTA (0.60) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL2119320 | 0.84 | FNTA (0.60) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL2119321 | 0.84 | FNTA (0.60) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL9522113 | 0.80 | NFKB1 (0.48) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL9521818 | 0.80 | NFKB1 (0.59) | KCNH2NFKB1NFKB2RELAFNTA | |
| SCHEMBL9521808 | 0.80 | NFKB1 (0.59) | KCNH2NFKB1NFKB2RELAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | claimed |