Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP5 | P51878 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521943 | 0.85 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL9522684 | 0.80 | KCNH2 (0.49) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9521451 | 0.80 | KCNH2 (0.49) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9524808 | 0.79 | KDM4E (0.47) | NFKB1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9521538 | 0.78 | NFKB1 (0.36) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9717205 | 0.77 | NFKB1 (0.50) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9522974 | 0.77 | NFKB1 (0.58) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9522979 | 0.77 | NFKB1 (0.58) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9360633 | 0.75 | NFKB1 (0.47) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9360627 | 0.75 | NFKB1 (0.47) | NFKB1KCNH2NFKB2RELAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474668-B1 | CONVERSION OF DELTA 16-STEROID TO A DELTA 17(20)-20-SILYL ETHER | THE UPJOHN COMPANY (US) | 1993-08-25 | — | — | EP | claimed |
| US-4975536-A | Conversion of a delta16-steroid to a delta17(20)-20-silyl ether | THE UPJOHN COMPANY (US) | 1990-12-04 | — | — | US | claimed |