Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522825 | 1.00 | MAPT (0.47) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12308077 | 0.82 | ALDH1A1 (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL6920981 | 0.81 | MAPT (0.61) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL497231 | 0.81 | MAPT (0.61) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL10363716 | 0.81 | ALDH1A1 (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9116813 | 0.81 | ALDH1A1 (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL10363717 | 0.81 | ALDH1A1 (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Dacisteine SCHEMBL2402188 | 0.80 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Dacisteine SCHEMBL1814125 | 0.80 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL11555294 | 0.79 | ALDH1A1 (0.50) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301474-B1 | NEW CYSTEINE DERIVATIVES HAVING EXPECTORANT ACTIVITY | MAGIS FARMACEUTICI S.P.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| US-4910222-A | Bronchodilator | MAGIS FARMACEUTICI SPA (IT) | 1990-03-20 | — | — | US | disclosed |
| EP-0301474-A2 | New cysteine derivatives having expectorant activity | MAGIS FARMACEUTICI S.P.A. (IT) | 1989-02-01 | — | — | EP | disclosed |