Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dacisteine SCHEMBL1814125 | 1.00 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL8918473 | 0.88 | NOD1 (0.49) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL10564990 | 0.85 | MAPT (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2403433 | 0.84 | MAPT (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12308075 | 0.84 | TGFBR1 (0.43) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL24067699 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13921443 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL6308419 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308082 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL4952983 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636311-B2 | Topically administered strontium-containing complexes for treating pain, pruritis and inflammation | GALLEON LABS LLC (US) | 2026-05-26 | — | — | US | claimed |
| US-20250099498-A1 | STRONTIUM BASED COMPOSITIONS AND FORMULATIONS FOR PAIN, PRURITUS, AND INFLAMMATION | GALLEON LABS LLC (US) | 2025-03-27 | — | — | US | claimed |
| US-12121536-B2 | Strontium based compositions and formulations for pain, pruritus, and inflammation | GALLEON LABS LLC (US) | 2024-10-22 | — | — | US | claimed |
| US-20240041919-A1 | TOPICALLY ADMINISTERED STRONTIUM-CONTAINING COMPLEXES FOR TREATING PAIN, PRURITIS AND INFLAMMATION | GALLEON LABS LLC | 2024-02-08 | — | — | US | claimed |
| US-20220323485-A1 | STRONTIUM BASED COMPOSITIONS AND FORMULATIONS FOR PAIN, PRURITUS, AND INFLAMMATION | PIKE, JOSEPH D. | 2022-10-13 | — | — | US | claimed |
| EP-2827847-B1 | TOPICALLY ADMINISTERED STRONTIUM-CONTAINING COMPLEXES FOR TREATING PAIN, PRURITIS AND INFLAMMATION | GALLEON LABS LLC (US) | 2022-09-14 | — | — | EP | claimed |
| EP-3284462-B1 | STRONTIUM BASED COMPOSITIONS AND FORMULATIONS FOR PAIN, PRURITUS, AND INFLAMMATION | GALLEON LABS LLC (US) | 2022-08-03 | — | — | EP | claimed |
| US-11235002-B2 | Strontium based compositions and formulations for pain, pruritus, and inflammation | GALLEON LABS LLC (US) | 2022-02-01 | — | — | US | claimed |
| US-20210177888-A1 | TOPICALLY ADMINISTERED STRONTIUM-CONTAINING COMPLEXES FOR TREATING PAIN, PRURITIS AND INFLAMMATION | JOSEPH D. PIKE | 2021-06-17 | — | — | US | claimed |
| US-20190269720-A1 | STRONTIUM BASED COMPOSITIONS AND FORMULATIONS FOR PAIN, PRURITUS, AND INFLAMMATION | PIKE, JOSEPH D. | 2019-09-05 | — | — | US | claimed |
| US-20030158118-A1 | Combination of cimetidine and cysteine derivatives for treating cancer | WEIDNER MORTEN SLOTH (DK) | 2003-08-21 | — | — | US | claimed |
| WO-2003045359-A2 | COMBINATION OF CIMETIDINE AND CYSTEINE DERIVATIVES FOR TREATING CANCER | ASTION ONCOLOGY APS (DK) | 2003-06-05 | — | — | WO | claimed |
| US-20030095959-A1 | Topical skin composition | ACCESS BUSINESS GROUP INTERNATIONAL LLC. | 2003-05-22 | — | — | US | claimed |
| WO-2003002125-A2 | COMBINATION OF AMINOSUGARS AND CYSTEINE OR CYSTEINE DERIVATIVES | ASTION A/S (DK) | 2003-01-09 | — | — | WO | claimed |
| EP-1231886-A1 | TOPICAL SKIN COMPOSITION | Alticor Inc. (US) | 2002-08-21 | — | — | EP | claimed |
| WO-2001037788-A1 | TOPICAL SKIN COMPOSITION | ALTICOR INC. (US) | 2001-05-31 | — | — | WO | claimed |
| EP-0716601-B1 | USE OF N,S-DIACETYLCYSTEINE-ETHYLESTER (DACEE) FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF VIRAL DISEASES | LUDWIG WEISS DR (DE) | 2000-06-28 | — | — | EP | claimed |
| US-5728373-A | EXHIBITING DEEP SKIN PENETRATION | BEIERSDORF AG (DE) | 1998-03-17 | — | — | US | claimed |
| EP-0656774-B1 | COSMETIC AND DERMATOLOGICAL SUNSCREEN COMPOSITIONS CONTAINING THIOLS AND/OR THIOL DERIVATES | BEIERSDORF AG (DE) | 1997-01-22 | — | — | EP | claimed |
| US-4405638-A | ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1983-09-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158118-A1 | Combination of cimetidine and cysteine derivatives for treating cancer | MGMT, CMA1, CYSLTR2 | MAPT 4793/4885KDM4E 2224/4885THRB 4256/4885 |
| US-12636311-B2 | Topically administered strontium-containing complexes for treating pain, pruritis and inflammation | SUCNR1, TRPV1, TRPV2 | MAPT 1603/4885KDM4E 1637/4885THRB 3354/4885 |
| US-20030095959-A1 | Topical skin composition | CUTA, S100A4, KRT18 | MAPT 1787/4885KDM4E 4634/4885THRB 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.