Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664387 | 0.77 | — | — | |
| SCHEMBL9820567 | 0.76 | — | — | |
| SCHEMBL9332302 | 0.76 | GSK3A (0.39) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL10662380 | 0.74 | — | — | |
| SCHEMBL7471758 | 0.73 | — | — | |
| SCHEMBL9665293 | 0.73 | MMP1 (0.32) | — | |
| SCHEMBL9354170 | 0.72 | — | — | |
| SCHEMBL9664837 | 0.72 | — | — | |
| SCHEMBL10660004 | 0.70 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7469481 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271916-B1 | ANTIBACTERIAL AGENT FOR MAMMAL USE COMPRISING CEPHALOSPORIN DERIVATIVES AS AN EFFECTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0193858-B1 | NEW 1-OXA-1-DETHIA-CEPHALOSPORIN COMPOUNDS AND ANTIBACTERIAL AGENT COMPRISING THE SAME | MERCK & CO. INC. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0367124-A1 | Penicillanic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-05-09 | — | — | EP | disclosed |
| US-4810702-A | Antibacterial agent for mammal use comprising cephalosporin derivatives as an effective ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4645769-A | 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same | MERCK & CO., INC. (US) | 1987-02-24 | — | — | US | disclosed |