SCHEMBL9664387

SCHEMBL9664387

O=C1CC(=S)C=CN1CCF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9522908 0.77 ALDH1A1 (0.32)
SCHEMBL9820567 0.76
SCHEMBL9664837 0.76
SCHEMBL10662380 0.71
SCHEMBL9665293 0.70 MMP1 (0.32)
SCHEMBL9354170 0.70
SCHEMBL9820605 0.69
SCHEMBL10660004 0.64 NPC1 (0.35)
SCHEMBL7471758 0.63
SCHEMBL7469481 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209751-B1 CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1992-09-16 EP disclosed
EP-0193858-B1 NEW 1-OXA-1-DETHIA-CEPHALOSPORIN COMPOUNDS AND ANTIBACTERIAL AGENT COMPRISING THE SAME MERCK & CO. INC. (US) 1991-11-27 EP disclosed
US-4758557-A Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA, LTD. (JP) 1988-07-19 US disclosed
US-4645769-A 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same MERCK & CO., INC. (US) 1987-02-24 US disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed
EP-0193858-A1 New 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same MERCK & CO. INC. (US) 1986-09-10 EP disclosed