Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524783 | 0.94 | MEN1 (0.39) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL7456661 | 0.75 | L3MBTL1 (0.42) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL9673263 | 0.70 | MEN1 (0.53) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL9526652 | 0.66 | DYRK1A (0.41) | NPC1RAB9A | |
| SCHEMBL11920854 | 0.66 | KMT2A (0.46) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL30763935 | 0.66 | MEN1 (0.44) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL11024894 | 0.66 | MEN1 (0.54) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL10174978 | 0.66 | KDM4C (0.46) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL7452792 | 0.66 | KDM4C (0.44) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL2376430 | 0.66 | KDM4C (0.42) | MEN1KMT2AKDM4CL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249170-B1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4921851-A | Cephem compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0249170-A2 | Cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-16 | — | — | EP | disclosed |