Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736441 | 0.81 | MAPT (0.57) | POLBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9447751 | 0.81 | MAPT (0.68) | POLBMAPTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL11481303 | 0.79 | PTGS1 (0.48) | POLBMAPTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL7740431 | 0.79 | POLB (0.45) | POLBMAPTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9577809 | 0.79 | MAPT (0.55) | POLBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| Acetic Acid SCHEMBL29786178 | 0.78 | KDM4E (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6111717 | 0.77 | EP300 (0.61) | EP300KAT2BKAT8MAPTMEN1 | |
| SCHEMBL28927027 | 0.77 | MAPT (0.53) | POLBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| Sulfuric Acid SCHEMBL3319379 | 0.75 | KDM4E (0.47) | POLBMAPTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL7745227 | 0.74 | MAPT (0.69) | POLBKAT2BMAPTSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359618-B1 | 2-SUBSTITUTED PARA-AMINOPHENOLS AND THEIR USE IN THE COLORATION OF KERATINIC FIBRES | L'OREAL (FR) | 1993-03-17 | — | — | EP | disclosed |
| EP-0359618-A1 | 2-Substituted para-aminophenols and their use in the coloration of keratinic fibres | L'OREAL (FR) | 1990-03-21 | — | — | EP | disclosed |
| EP-0294669-A1 | Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair | L'OREAL (FR) | 1988-12-14 | — | — | EP | disclosed |