Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201094 | 0.81 | MAPT (0.52) | MAPTSMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL9447751 | 0.81 | MAPT (0.68) | POLBMAPTPKMSMN1; SMN2HTT | |
| SCHEMBL11481303 | 0.79 | PTGS1 (0.48) | POLBMAPTPKMSMN1; SMN2HTT | |
| SCHEMBL7740716 | 0.79 | HDAC3 (0.41) | MAPTHTTGAAALDH1A1L3MBTL1 | |
| SCHEMBL9522975 | 0.79 | POLB (0.45) | POLBMAPTPKMSMN1; SMN2HTT | |
| SCHEMBL7741236 | 0.78 | GAA (0.46) | POLBMAPTPKMSMN1; SMN2GAA | |
| SCHEMBL29396266 | 0.77 | KEAP1 (0.55) | MAPTHTTGAAALDH1A1L3MBTL1 | |
| SCHEMBL449212 | 0.77 | KEAP1 (0.55) | MAPTHTTGAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8118011 | 0.76 | KEAP1 (0.53) | MAPTHTTGAAALDH1A1L3MBTL1 | |
| SCHEMBL7745227 | 0.74 | MAPT (0.69) | POLBMAPTPKMSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |