Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976616 | 0.90 | ALDH1A1 (0.53) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9523354 | 0.88 | PRKD3 (0.48) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9525097 | 0.87 | PRKD3 (0.47) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9522724 | 0.87 | LMNA (0.39) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9522977 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9522013 | 0.85 | ALDH1A1 (0.55) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9522474 | 0.85 | KDM4E (0.50) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10744214 | 0.83 | LMNA (0.52) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8323537 | 0.82 | PIM1 (0.41) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10772867 | 0.82 | KCNH2 (0.44) | LMNAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |