Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316649 | 0.94 | RHEB (0.41) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL23051806 | 0.85 | TDP1 (0.49) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL6476374 | 0.84 | GAA (0.42) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL9261531 | 0.83 | TUBB4A (0.40) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL8768218 | 0.82 | FABP6 (0.58) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL29215311 | 0.81 | BRD4 (0.45) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL6217370 | 0.78 | HTT (0.64) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL6217364 | 0.78 | KDM4E (0.50) | RHEBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8314626 | 0.77 | TUBB4A (0.40) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL8768199 | 0.77 | FABP6 (0.58) | RHEBMAPTKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129409-B1 | Thiazolo - and thiazinobenzimidazoles | WYETH JOHN & BROTHER LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-4873237-A | ANTIULCER AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1989-10-10 | — | — | US | disclosed |
| EP-0129409-A2 | Thiazolo - and thiazinobenzimidazoles | JOHN WYETH & BROTHER LIMITED (GB) | 1984-12-27 | — | — | EP | disclosed |