SCHEMBL952338

SCHEMBL952338

N#Cc1ccc(C(F)(F)F)cc1Cl

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 9/20 0.65
MRGPRX4 Q96LA9 2/20 0.54
TRPV4 Q9HBA0 2/20 0.52
PDE2A O00408 1/20 0.44
CYP11B2 P19099 1/20 0.44
SLC22A12 Q96S37 1/20 0.43
KIF11 P52732 1/20 0.42
TAS2R14 Q9NYV8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1571556 0.86 AR (0.51) ARMRGPRX4TRPV4SLC22A12TAS2R14
SCHEMBL384969 0.84 AR (0.47) ARMRGPRX4PDE2ASLC22A12KIF11
SCHEMBL29837271 0.84 AR (0.47) ARMRGPRX4PDE2ASLC22A12KIF11
SCHEMBL11875183 0.82 AR (0.57) ARMRGPRX4TRPV4CYP11B2SLC22A12
SCHEMBL9205171 0.81 CYP11B2 (0.50) ARCYP11B2
SCHEMBL12151755 0.81 AR (0.52) ARCYP11B2KIF11TAS2R14
SCHEMBL29546917 0.81 AR (0.52) ARCYP11B2KIF11TAS2R14
SCHEMBL2555215 0.80 AR (0.65) ARTRPV4CYP11B2SLC22A12KIF11
SCHEMBL31568536 0.80 PDE2A (0.44) ARMRGPRX4PDE2A
SCHEMBL15541043 0.80 PDE2A (0.44) ARMRGPRX4PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184597-A Preparation method of isoxaflutole 北京颖泰嘉和生物科技股份有限公司 2024-06-14 CN claimed
CN-118146127-A Preparation method of 2-methylthio-4-trifluoromethyl benzonitrile 北京颖泰嘉和生物科技股份有限公司 2024-06-07 CN claimed
CN-114149365-B Process control method for synthesizing 3-cyano-2, 6-dihydroxy-4-trifluoromethyl pyridine triethylamine salt 江苏中旗科技股份有限公司 2024-03-19 CN claimed
CN-217120226-U Production system of isoxazole compound 内蒙古蓝科生物科技有限公司 2022-08-05 CN claimed
CN-114149365-A Process control method for synthesizing 3-cyano-2, 6-dihydroxy-4-trifluoromethylpyridine triethylamine salt 江苏中旗科技股份有限公司 2022-03-08 CN claimed
CN-106225213-A Thermal coupling device control system and control method thereof in a kind of megastore water system 江苏建筑职业技术学院 2016-12-14 CN claimed
CN-103087054-A 4-pyridyl phenyl ether compounds, and preparation method and application thereof UNIV SHANDONG 2013-05-08 CN claimed
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND SHOUYAO HOLDINGS BEIJING CO LTD (CN) 2025-07-10 US disclosed
EP-4501912-A1 NOVEL HETEROCYCLIC COMPOUND Shouyao Holdings (Beijing) Co., Ltd. (CN) 2025-02-05 EP disclosed
CN-118475560-A Novel heterocyclic compound 首药控股(北京)股份有限公司 2024-08-09 CN disclosed
CN-118184597-A Preparation method of isoxaflutole 北京颖泰嘉和生物科技股份有限公司 2024-06-14 CN disclosed
CN-118184597-A Preparation method of isoxaflutole 北京颖泰嘉和生物科技股份有限公司 2024-06-14 CN disclosed
CN-118146127-A Preparation method of 2-methylthio-4-trifluoromethyl benzonitrile 北京颖泰嘉和生物科技股份有限公司 2024-06-07 CN disclosed
CN-1188476-A 4-phenylaminothiazole derivatives, method for preparing same, and pharmaceutical compositions thereof SANOFI SA (FR) 1998-07-22 CN disclosed
EP-0853085-A1 Piperidine derivatives having anxiolytic effect H. LUNDBECK A/S (DK) 1998-07-15 EP disclosed
US-5665725-A Piperidine derivatives having anxiolytic effect Lundbeck, H. (DK) 1997-09-09 US disclosed
WO-1997024318-A1 METHOD FOR SYNTHESIS OF AN AROMATIC DERIVATIVE SUBSTITUTED BY A HALOGEN ATOM OTHER THAN FLUORINE AND BY A CYANO GROUP RHODIA CHIMIE (FR) 1997-07-10 WO disclosed
EP-0593511-A1 PIPERIDINE DERIVATES HAVING ANXIOLYTIC EFFECT H. LUNDBECK A/S (DK) 1994-04-27 EP disclosed
WO-1992022554-A1 PIPERIDINE DERIVATES HAVING ANXIOLYTIC EFFECT H. LUNDBECK A/S (DK) 1992-12-23 WO disclosed
EP-0518805-A1 Piperidine derivatives H. LUNDBECK A/S (DK) 1992-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND MAPT, MNAT1, MAT2A AR 1962/4885MRGPRX4 1140/4885TRPV4 2728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.