SCHEMBL9523402

SCHEMBL9523402

Cc1ccc(S(=O)(=O)OCCOc2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA9 Q16790 1/20 0.54
FFAR1 O14842 1/20 0.52
NR3C1 P04150 1/20 0.49
LTA4H P09960 4/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
DRD2 P14416 2/20 0.47
DRD4 P21917 2/20 0.47
DRD3 P35462 2/20 0.47
CACNA1B Q00975 1/20 0.46
LMNA P02545 2/20 0.46
CASP3 P42574 1/20 0.45
CASP7 P55210 1/20 0.45
SOS1 Q07889 1/20 0.45
PLA2G2A P14555 1/20 0.45
FFAR4 Q5NUL3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395593 0.94 CA12 (0.55) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL6914766 0.90 CA12 (0.52) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL8069545 0.89 CA12 (0.63) HTTSMN1; SMN2CA12CA1CA9
Acetonitrile SCHEMBL27788037 0.87 CA12 (0.50) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL1109820 0.87 DRD2 (0.50) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL19326867 0.86 CA12 (0.52) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL31618044 0.84 HTT (0.59) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL9713577 0.84 CA12 (0.53) HTTSMN1; SMN2CA12CA1CA9
SCHEMBL10346036 0.84 CA12 (0.57) SMN1; SMN2CA12CA1CA9TDP1
SCHEMBL5638579 0.84 CA12 (0.57) HTTSMN1; SMN2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0289919-B1 N-SUBSTITUTED AZOLES BASF Aktiengesellschaft (DE) 1993-03-17 EP disclosed
EP-0289919-A2 N-Substituted azoles BASF Aktiengesellschaft (DE) 1988-11-09 EP disclosed
EP-0089115-B1 OXIME ETHERS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-22 EP disclosed
US-4514406-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-30 US disclosed
EP-0089115-A1 Oxime ethers, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-09-21 EP disclosed