SCHEMBL6914766

SCHEMBL6914766

Cc1ccc(S(=O)(=O)OCCOCCOc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA9 Q16790 1/20 0.52
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
DRD2 P14416 2/20 0.44
DRD4 P21917 2/20 0.44
DRD3 P35462 2/20 0.44
CASP3 P42574 1/20 0.44
CASP7 P55210 1/20 0.44
KMT2A Q03164 3/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
RAB9A P51151 1/20 0.43
AR P10275 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 2/20 0.42
CNR2 P34972 1/20 0.41
PKM P14618 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395593 0.95 CA12 (0.55) CA12CA1CA9HTTSMN1; SMN2
SCHEMBL9523402 0.90 HTT (0.60) CA12CA1CA9HTTSMN1; SMN2
Acetonitrile SCHEMBL27788037 0.89 CA12 (0.50) CA12CA1CA9HTTSMN1; SMN2
SCHEMBL1109820 0.88 DRD2 (0.50) CA12CA1CA9HTTSMN1; SMN2
SCHEMBL8069545 0.88 CA12 (0.63) CA12CA1CA9HTTSMN1; SMN2
SCHEMBL22491454 0.87 CA12 (0.54) CA12CA1CA9SMN1; SMN2DRD2
SCHEMBL20128984 0.87 CA12 (0.54) CA12CA1CA9SMN1; SMN2DRD2
SCHEMBL31748240 0.86 CA12 (0.49) CA12CA1CA9AR
SCHEMBL24302708 0.86 CA12 (0.53) CA12CA1CA9SMN1; SMN2KMT2A
SCHEMBL881292 0.86 ALDH1A1 (0.53) CA12CA1CA9HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed