Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695219 | 0.79 | ACHE (0.70) | ACHECYP2D6NR1I2LMNAADRA2A | |
| SCHEMBL10441538 | 0.79 | CYP2D6 (0.61) | ACHECYP2D6NR1I2LMNAADRA2A | |
| SCHEMBL9858161 | 0.78 | CYP2D6 (0.74) | ACHECYP2D6NR1I2LMNAADRA2A | |
| SCHEMBL9721972 | 0.78 | CYP2D6 (0.74) | ACHECYP2D6NR1I2LMNAADRA2A | |
| Butenafine SCHEMBL20456391 | 0.77 | CYP2D6 (1.00) | ACHECYP2D6NR1I2LMNAADRA2A | |
| Butenafine SCHEMBL29354083 | 0.77 | CYP2D6 (1.00) | ACHECYP2D6NR1I2LMNAADRA2A | |
| Butenafine SCHEMBL65526 | 0.77 | CYP2D6 (1.00) | ACHECYP2D6NR1I2LMNAADRA2A | |
| SCHEMBL10932466 | 0.77 | CYP2D6 (1.00) | ACHECYP2D6NR1I2LMNAADRA2A | |
| SCHEMBL9722034 | 0.76 | CYP2D6 (0.72) | ACHECYP2D6NR1I2LMNAADRA2A | |
| SCHEMBL9722021 | 0.76 | CYP2D6 (0.72) | ACHECYP2D6NR1I2LMNAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396769-B1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5093480-A | Fungicides | KOWA COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0396769-A1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1990-11-14 | — | — | EP | disclosed |