Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523458 | 1.00 | LMNA (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9523899 | 0.90 | HSD17B10 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9522999 | 0.90 | HSD17B10 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL8290713 | 0.88 | ALDH1A1 (0.65) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9522255 | 0.86 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9522330 | 0.86 | MAPT (0.54) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9522428 | 0.86 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL10462493 | 0.86 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9523579 | 0.86 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL9522459 | 0.86 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315698-B1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4960770-A | Vasodilating agents, cardiovascular disorder | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0315698-A1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |