Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | BCL9 | O00512 | 1/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056331 | 0.88 | KMT2A (0.53) | KMT2ABCL9CTNNB1MEN1MAPT | |
| SCHEMBL5729901 | 0.86 | BCL9 (0.65) | KMT2ABCL9CTNNB1MEN1MAPT | |
| SCHEMBL4389354 | 0.83 | KMT2A (0.55) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3281488 | 0.82 | MAPT (0.69) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16056068 | 0.81 | BCL9 (0.65) | KMT2ABCL9CTNNB1MEN1MAPT | |
| SCHEMBL5022220 | 0.81 | HTR2A (0.63) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28060070 | 0.80 | BCL9 (0.60) | KMT2ABCL9CTNNB1MEN1MAPT | |
| SCHEMBL9827799 | 0.80 | KMT2A (0.59) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6554205 | 0.80 | KMT2A (0.57) | KMT2ABCL9CTNNB1MEN1MAPT | |
| SCHEMBL5957779 | 0.80 | KMT2A (0.62) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |