Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056068 | 0.85 | BCL9 (0.65) | BCL9CTNNB1ALDH1A1PTPN7PTPN12 | |
| SCHEMBL6659906 | 0.85 | BCL9 (0.64) | BCL9CTNNB1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL28122438 | 0.82 | KMT2A (0.60) | ALDH1A1KMT2AMEN1GAA | |
| Phenyl Propionic Acid SCHEMBL11756556 | 0.82 | ALDH1A1 (0.60) | BCL9CTNNB1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6400861 | 0.81 | HTR2A (0.61) | BCL9CTNNB1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5729901 | 0.80 | BCL9 (0.65) | BCL9CTNNB1ALDH1A1MAPTKMT2A | |
| SCHEMBL9523677 | 0.80 | KMT2A (0.60) | BCL9CTNNB1ALDH1A1MAPTKMT2A | |
| SCHEMBL16139291 | 0.80 | MGLL (0.55) | BCL9CTNNB1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL957930 | 0.79 | BCL9 (0.81) | BCL9CTNNB1ALDH1A1NPSR1PTPN7 | |
| SCHEMBL12715327 | 0.79 | BCL9 (0.62) | BCL9CTNNB1ALDH1A1PTPN7PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473559-A | Activation of carbonyl [beta]-carbons for chemical transformations | UNIV NANYANG TECH | 2016-04-06 | — | — | CN | disclosed |