Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523720 | 0.92 | MEN1 (0.37) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9316085 | 0.92 | MAPT (0.37) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL9522378 | 0.90 | RIPK1 (0.38) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9525898 | 0.89 | MAPT (0.40) | ALDH1A1KMT2AHPGDNPSR1KDM4E | |
| SCHEMBL9522532 | 0.88 | MAPT (0.39) | ALDH1A1HPGDNPSR1KDM4ELMNA | |
| SCHEMBL9525574 | 0.88 | LMNA (0.37) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9316548 | 0.87 | MEN1 (0.40) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9316080 | 0.85 | TP53 (0.37) | CA1CA2LMNAMAPTTP53 | |
| SCHEMBL9834297 | 0.83 | MAPK14 (0.40) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9522374 | 0.82 | RIPK1 (0.39) | ALDH1A1KMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420883-B1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5166152-A | Immunostimulants, bactericides, viricides, antitumor agents | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-11-24 | — | — | US | disclosed |