Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 11/20 | 0.42 |
| ▸ | EDNRA | P25101 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975735 | 0.88 | EDNRB (0.47) | EDNRBEDNRAKMT2AKCNN4TP53 | |
| SCHEMBL8975656 | 0.78 | EDNRB (0.49) | EDNRBEDNRAKMT2AMAPT | |
| SCHEMBL8871463 | 0.72 | EDNRB (0.51) | EDNRBEDNRAKMT2AKCNN4TP53 | |
| SCHEMBL8873369 | 0.71 | EDNRB (0.49) | EDNRBEDNRAMEN1OPRM1OPRD1 | |
| SCHEMBL8975814 | 0.71 | EDNRB (0.47) | EDNRBEDNRAMEN1OPRM1OPRD1 | |
| SCHEMBL27972948 | 0.70 | KCNN4 (0.64) | MEN1OPRM1OPRD1KMT2AKCNN4 | |
| SCHEMBL8872002 | 0.68 | EDNRB (0.44) | EDNRBEDNRAMEN1OPRM1OPRD1 | |
| SCHEMBL4002098 | 0.65 | KCNN4 (0.56) | MEN1OPRM1OPRD1KMT2AKCNN4 | |
| SCHEMBL8976238 | 0.65 | ALDH1A1 (0.38) | EDNRBEDNRAMAPT | |
| SCHEMBL12095209 | 0.65 | EDNRB (0.52) | EDNRBEDNRAKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575404-A1 | HERBICIDES | AgrEvo UK Limited (GB) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016511-A1 | HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |