SCHEMBL9524037

SCHEMBL9524037

CO[C@H]1C(O)O[C@H]2[C@@H]1OC[C@H]2O

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4382444 0.82 THRB (0.44) THRBLMNAMAPTL3MBTL1
SCHEMBL6017729 0.82 THRB (0.44) THRBLMNAMAPTL3MBTL1
SCHEMBL372049 0.82 THRB (0.44) THRBLMNAMAPTL3MBTL1
SCHEMBL21474408 0.75
SCHEMBL8218813 0.74 L3MBTL1 (0.38) THRBLMNAL3MBTL1
Isosorbide SCHEMBL301880 0.73 THRB (0.77) THRBLMNAMAPT
SCHEMBL7147367 0.72 THRB (0.46) THRBLMNAMAPTL3MBTL1
SCHEMBL7154485 0.72 THRB (0.46) THRBLMNAMAPTL3MBTL1
SCHEMBL7643794 0.72 THRB (0.46) THRBLMNAMAPTL3MBTL1
SCHEMBL7156047 0.72 L3MBTL1 (0.39) THRBLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323994-B1 PROCESS FOR PREPARING ANHYDRIDES OF HEXITOLS, HEXONOLACTONES, HEXOSES AND HEXOSIDES ERIDANIA BEGHIN-SAY (FR) 1993-03-31 EP disclosed
WO-1989000162-A1 PROCESS FOR PREPARING ANHYDRIDES OF HEXITOLS, HEXONOLACTONES, HEXOSES AND HEXOSIDES BEGHIN-SAY, S.A. (FR) 1989-01-12 WO disclosed