Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525721 | 0.79 | HTT (0.47) | ALDH1A1ACHEHTTSMN1; SMN2GAA | |
| SCHEMBL9528622 | 0.79 | HCAR2 (0.49) | ALDH1A1ACHEHTTSMN1; SMN2GAA | |
| SCHEMBL9525371 | 0.74 | HTT (0.74) | ALDH1A1HTTSMN1; SMN2GAATSHR | |
| SCHEMBL9524303 | 0.73 | HTT (0.50) | ALDH1A1HTTSMN1; SMN2GAATSHR | |
| SCHEMBL7751510 | 0.73 | ADRA2C (0.69) | ALDH1A1ACHEHTTSMN1; SMN2GAA | |
| SCHEMBL11724515 | 0.72 | KMT2A (0.50) | ALDH1A1ATMHTTSMN1; SMN2GAA | |
| SCHEMBL10525429 | 0.72 | ALDH1A1 (0.72) | ALDH1A1ATMHTTSMN1; SMN2TSHR | |
| SCHEMBL735945 | 0.72 | ATM (0.59) | ALDH1A1ATMACHEHTTSMN1; SMN2 | |
| SCHEMBL6325991 | 0.72 | ALDH1A1 (0.60) | ALDH1A1ATMHTTSMN1; SMN2GAA | |
| SCHEMBL11728283 | 0.72 | ALDH1A1 (0.46) | ALDH1A1GAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |