Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524269 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL2353249 | 0.78 | CYP19A1 (0.63) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL9261186 | 0.77 | CYP11B2 (0.63) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL13529263 | 0.76 | CYP19A1 (0.66) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL13529262 | 0.76 | CYP19A1 (0.66) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL9256368 | 0.75 | CYP11B2 (0.73) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL14769100 | 0.75 | CYP19A1 (0.73) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| Fadrozole SCHEMBL25491 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| Dexfadrostat SCHEMBL685516 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| Fadrozole SCHEMBL3295820 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356673-B1 | Substituted 5,6,7,8-tetrahydroimidazo[1,5-a]pyridines and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-05-19 | — | — | EP | disclosed |