Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567506 | 0.91 | MEN1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9522639 | 0.89 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9523011 | 0.89 | LMNA (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9522285 | 0.82 | LMNA (0.57) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9522681 | 0.82 | KDM4E (0.45) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9525435 | 0.81 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9522092 | 0.81 | PRKD3 (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9523618 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9232091 | 0.81 | LMNA (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9231555 | 0.81 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |