Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231555 | 0.94 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9232091 | 0.94 | LMNA (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9229211 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9522285 | 0.90 | LMNA (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9521872 | 0.89 | LMNA (0.56) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9229755 | 0.88 | LMNA (0.44) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9233955 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9228616 | 0.86 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9233927 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9523011 | 0.85 | LMNA (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |