⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040697 | 0.78 | — | — | |
| SCHEMBL7907029 | 0.75 | — | — | |
| SCHEMBL2654037 | 0.72 | — | — | |
| SCHEMBL2086711 | 0.70 | DGAT1 (0.37) | — | |
| SCHEMBL2791142 | 0.69 | — | — | |
| SCHEMBL3067654 | 0.67 | — | — | |
| SCHEMBL2972384 | 0.67 | — | — | |
| SCHEMBL2587467 | 0.67 | — | — | |
| SCHEMBL27954012 | 0.65 | — | — | |
| SCHEMBL23829821 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431008-A4 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | — | 1992-03-11 | — | — | EP | claimed |
| US-5091523-A | Bactericides, antitumor agent | GEORGETOWN UNIVERSITY (US) | 1992-02-25 | — | — | US | claimed |
| EP-0431008-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1991-06-12 | — | — | EP | claimed |
| WO-1990001931-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1990-03-08 | — | — | WO | claimed |
| EP-0533692-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0431008-A4 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | — | 1992-03-11 | — | — | EP | disclosed |
| US-5091523-A | Bactericides, antitumor agent | GEORGETOWN UNIVERSITY (US) | 1992-02-25 | — | — | US | disclosed |
| WO-1991016049-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1991-10-31 | — | — | WO | disclosed |
| EP-0431008-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990001931-A1 | MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1990-03-08 | — | — | WO | disclosed |