Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524328 | 1.00 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL6727745 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL10134035 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL13665937 | 0.79 | KMT2A (0.83) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL11879188 | 0.77 | MAPT (0.54) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL13665916 | 0.76 | KMT2A (0.66) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL6952167 | 0.75 | KDM4E (0.68) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL6952163 | 0.75 | KDM4E (0.68) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL23607022 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPTTDP1HPGD | |
| SCHEMBL13665917 | 0.73 | KMT2A (0.61) | ALDH1A1KMT2AMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | claimed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | claimed |
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |