Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521119 | 0.83 | MAOB (0.45) | HTTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29009279 | 0.70 | ALDH1A1 (0.53) | HTTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11853555 | 0.69 | ALDH1A1 (0.40) | HTTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8713714 | 0.68 | NPSR1 (0.36) | CYP1A2CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7268455 | 0.68 | HPGD (0.48) | HTTSMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL3758807 | 0.68 | ALDH1A1 (0.60) | HTTPOLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL292834 | 0.68 | ALDH1A1 (0.60) | HTTPOLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19514751 | 0.67 | POLB (0.49) | HTTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4710453 | 0.67 | SMN1; SMN2 (0.69) | HTTCYP1A2CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL6403295 | 0.66 | ALDH1A1 (0.58) | HTTPOLBSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249170-B1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4921851-A | Cephem compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0249170-A2 | Cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-16 | — | — | EP | disclosed |
| US-4546176-A | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same | EISAI CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |